AutoICD API

84916-6

Laboratory

Cells.chromosome region 17p13.1 deletion/Cells counted in Blood or Tissue by FISH

Definition

Deletions at 17p13.1 involving the TP53 gene can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma as well as other forms of cancer. This term is used to report the number of cells that have the deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI p53 (17p13.1) probe, which targets the TP53 gene and flanking regions.

LOINC 6-Axis Classification

Component

Cells.chromosome region 17p13.1 deletion/Cells counted

Property

NFr

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Qn

Method Type

FISH

Details

Class

MOLPATH.DELDUP

Order/Observation

Both

Short Name

Cells.17p13.1 Del/Cells NFr Bld/T FISH

Display Name

Cells.chromosome region 17p13.1 del/Cells counted FISH (Bld/Tiss)

Related Names

BloodCellCells.17p13.1CellularityChr 17p13.1Chr 17p13.1 delChromosomChromosomesCyto locDelDeletionsFluorescent in situ hybridizationGeneticsHeredityHeritableInheritedMolecular pathologyMOLPATHMOLPATH.DELDUPNumber FractionPercentPoint in timeQNTQuanQuantQuantitativeRandomTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 84916-6?

LOINC code 84916-6 identifies "Cells.chromosome region 17p13.1 deletion/Cells counted in Blood or Tissue by FISH". Deletions at 17p13.1 involving the TP53 gene can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma as well as other forms of cancer. This term is used to report the number of cells that have the deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI p53 (17p13.1) probe, which targets the TP53 gene and flanking regions.

What does 84916-6 measure?

This code measures Cells.chromosome region 17p13.1 deletion/Cells counted in Bld/Tiss. It belongs to the MOLPATH.DELDUP class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.