AutoICD API

82532-3

Laboratory

SDHB and SDHC and SDHD gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method

Definition

Full sequencing analysis of all coding exons and intron/exon boundaries of the SDHB, SDHC and SDHD genes is performed along with large deletion/duplication analysis by methods such as multiplex ligation-dependent probe amplification (MLPA). This test is performed to aid in the diagnosis of hereditary paraganglioma-pheochromocytoma syndrome associated with pathogenic variants in one of these genes.

LOINC 6-Axis Classification

Component

SDHB & SDHC & SDHD gene deletion+duplication & full mutation analysis

Property

Find

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Doc

Method Type

Molgen

Details

Class

MOLPATH

Order/Observation

Both

Short Name

SDHB+SDHC+SDHD Del+Dup + Full Mut Bld/T

Display Name

SDHB and SDHC and SDHD gene del+dup and full mutation analysis Molgen Doc (Bld/Tiss)

Related Names

AmplificationBloodCBT1CII-4CWS3cybSDelDel+DupDel+Dup + Full Mut AnlDeletionsDocumentDpFindingFindingsfull gene sequencingFull Mut AnlGeneticsHeredityHeritableInheritedMolecular geneticsMolecular pathologyMOLPATHMutMutationsparaganglioma or familial glomus tumors 1PCRPGLPGL1Point in timeQPs3RandomSDH4SDHB+SDHC+SDHDsequencing of entire coding regionsuccinate dehydrogenase complex, subunit D, integral membrane proteinTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 82532-3?

LOINC code 82532-3 identifies "SDHB and SDHC and SDHD gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method". Full sequencing analysis of all coding exons and intron/exon boundaries of the SDHB, SDHC and SDHD genes is performed along with large deletion/duplication analysis by methods such as multiplex ligation-dependent probe amplification (MLPA). This test is performed to aid in the diagnosis of hereditary paraganglioma-pheochromocytoma syndrome associated with pathogenic variants in one of these genes.

What does 82532-3 measure?

This code measures SDHB & SDHC & SDHD gene deletion+duplication & full mutation analysis in Bld/Tiss. It belongs to the MOLPATH class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.