81759-3
LaboratoryLymphocyte proliferation.anti-CD28.maximum/CD45 in Blood by Flow cytometry (FC)
Definition
The percent of proliferating lymphocytes stimulated by anti-CD28 (aCD28) out of the total CD45 cell population. The maximum (highest proliferating out of 3 titrations) response to anti-CD28 is reported. This is a second-level test for assessing lymphocyte (T-cell) function after lymphocyte proliferation to phytohemagglutinin has been assessed. The test is used to evaluate patients with impairment in cellular immunity due to primary or secondary immunodeficiencies and in patients receiving immunosuppressive or immunomodulatory therapy.
LOINC 6-Axis Classification
Component
Lymphocyte proliferation.anti-CD28.maximum/CD45
Property
NFr
Time Aspect
Pt
System
Bld
Scale Type
Qn
Method Type
Flow cytometry
Details
Class
HEM/BC
Order/Observation
Observation
Short Name
LPT aCD28 max/CD45 NFr Bld FC
Display Name
Lymphocyte proliferation.anti-CD28.maximum/CD45 FC (Bld)
Related Names
Frequently Asked Questions
What is LOINC code 81759-3?
LOINC code 81759-3 identifies "Lymphocyte proliferation.anti-CD28.maximum/CD45 in Blood by Flow cytometry (FC)". The percent of proliferating lymphocytes stimulated by anti-CD28 (aCD28) out of the total CD45 cell population. The maximum (highest proliferating out of 3 titrations) response to anti-CD28 is reported. This is a second-level test for assessing lymphocyte (T-cell) function after lymphocyte proliferation to phytohemagglutinin has been assessed. The test is used to evaluate patients with impairment in cellular immunity due to primary or secondary immunodeficiencies and in patients receiving immunosuppressive or immunomodulatory therapy.
What does 81759-3 measure?
This code measures Lymphocyte proliferation.anti-CD28.maximum/CD45 in Bld. It belongs to the HEM/BC class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.