AutoICD API

81746-0

Laboratory

Chromosome region 17p13.1 deletion in Blood or Tissue by FISH

Definition

Deletions at 17p13.1 involving the TP53 gene can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma as well as other forms of cancer. Labs will report the number of cells that have the probe deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI p53 (17p13.1) probe, which targets the TP53 gene and flanking regions.

LOINC 6-Axis Classification

Component

Chromosome region 17p13.1 deletion

Property

Find

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Doc

Method Type

FISH

Details

Class

MOLPATH.DELDUP

Order/Observation

Both

Short Name

Chr 17p13.1 Del Bld/T FISH

Display Name

17p13.1 del FISH Doc (Bld/Tiss)

Related Names

BloodChr 17p13.1Chr 17p13.1 delChromosomChromosomesCyto locDelDeletionsDocumentFindingFindingsFluorescent in situ hybridizationGeneticsHeredityHeritableInheritedMolecular pathologyMOLPATHMOLPATH.DELDUPPoint in timeRandomTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 81746-0?

LOINC code 81746-0 identifies "Chromosome region 17p13.1 deletion in Blood or Tissue by FISH". Deletions at 17p13.1 involving the TP53 gene can be detected by FISH and used for the diagnosis of chronic lymphocytic leukemia (CLL), multiple myeloma as well as other forms of cancer. Labs will report the number of cells that have the probe deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI p53 (17p13.1) probe, which targets the TP53 gene and flanking regions.

What does 81746-0 measure?

This code measures Chromosome region 17p13.1 deletion in Bld/Tiss. It belongs to the MOLPATH.DELDUP class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.