80737-0

LOINC code 80737-0 identifies "Calculated panel reactive antibody - Serum". A patient's "calculated panel reactive antibody" (cPRA) determines the likelihood that a transplant recipient and donor would be incompatible. The cPRA is calculated based on how many and which HLA antibodies the patient has compared to known information about the HLA antigen frequencies from ~1200 donors from 2003-2005.[PMID: 19958328] The more antibodies the patient has and the more common the HLA antigens are in the donor pool, the higher the cPRA. Calculated cPRA is not the same as a patient's percent PRA, which is simply the percentage of a pool of donors (~100) to which a patient had reactive antibodies (see the HLA Ab panel [LOINC: 46993-2]). Note that "panel" is part of the antibody name and a single result is expected. This is not panel term.

This code measures Calculated panel reactive antibody in Ser. It belongs to the HLA class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.