80622-4
LaboratoryZika virus neutralizing antibody [Titer] in Serum by Neutralization test --1st specimen
Definition
Quantitative result for Zika virus neutralizing antibodies in acute phase serum. Serological cross-reactivity is strong between Zika and other flaviviruses, especially Dengue virus. Therefore, positive EIA or IF assays for Zika virus IgM antibodies are presumptive only and should be confirmed by a neutralization assay, such as the plaque-reduction neutralization test (PRNT), which can discriminate between Zika virus and cross-reacting antibodies in primary flavivirus infections. Recent Zika virus infection is confirmed by stable high neutralizing antibody titers, seroconversion, or a 4x or greater increases in neutralizing antibody titer in a patient's appropriately timed acute and convalescent phase sera.
LOINC 6-Axis Classification
Component
Zika virus Ab.Neut^1st specimen
Property
Titr
Time Aspect
Pt
System
Ser
Scale Type
SemiQn
Method Type
Neut
Details
Class
MICRO
Order/Observation
Both
Short Name
ZIKV NAb sp1 Titr Ser Nt
Display Name
ZIKV neut ab spec 1 Neut test (S) [Titer]
Related Names
Frequently Asked Questions
What is LOINC code 80622-4?
LOINC code 80622-4 identifies "Zika virus neutralizing antibody [Titer] in Serum by Neutralization test --1st specimen". Quantitative result for Zika virus neutralizing antibodies in acute phase serum. Serological cross-reactivity is strong between Zika and other flaviviruses, especially Dengue virus. Therefore, positive EIA or IF assays for Zika virus IgM antibodies are presumptive only and should be confirmed by a neutralization assay, such as the plaque-reduction neutralization test (PRNT), which can discriminate between Zika virus and cross-reacting antibodies in primary flavivirus infections. Recent Zika virus infection is confirmed by stable high neutralizing antibody titers, seroconversion, or a 4x or greater increases in neutralizing antibody titer in a patient's appropriately timed acute and convalescent phase sera.
What does 80622-4 measure?
This code measures Zika virus Ab.Neut^1st specimen in Ser. It belongs to the MICRO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.