80517-6
LaboratoryKappa light chains.free/Lambda light chains.free [Mass Ratio] in Serum by Nephelometry
Definition
An elevated kappa/lambda ratio supports the diagnosis of a monoclonal gammopathy and requires further investigation. Borderline elevated kappa/lambda ratios occur with renal impairment, and may require appropriate renal function tests. Elevated levels of both kappa and lambda with normal kappa/lambda ratio - may be due to (1) renal impairment (common); (2) Over-production of polyclonal FLC from inflammatory conditions (common); (3) Bi-clonal gammopathies of different free light chain types (rare).
LOINC 6-Axis Classification
Component
Immunoglobulin light chains.kappa.free/Immunoglobulin light chains.lambda.free
Property
MRto
Time Aspect
Pt
System
Ser
Scale Type
Qn
Method Type
Nephelometry
Details
Class
CHEM
Order/Observation
Observation
Short Name
Kappa LC Free/Lambda Free Ser Neph
Display Name
Immunoglobulin light chains.kappa.free/Immunoglobulin light chains.lambda.free Nephelometry (S) [Mass ratio]
Related Names
Frequently Asked Questions
What is LOINC code 80517-6?
LOINC code 80517-6 identifies "Kappa light chains.free/Lambda light chains.free [Mass Ratio] in Serum by Nephelometry". An elevated kappa/lambda ratio supports the diagnosis of a monoclonal gammopathy and requires further investigation. Borderline elevated kappa/lambda ratios occur with renal impairment, and may require appropriate renal function tests. Elevated levels of both kappa and lambda with normal kappa/lambda ratio - may be due to (1) renal impairment (common); (2) Over-production of polyclonal FLC from inflammatory conditions (common); (3) Bi-clonal gammopathies of different free light chain types (rare).
What does 80517-6 measure?
This code measures Immunoglobulin light chains.kappa.free/Immunoglobulin light chains.lambda.free in Ser. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.