AutoICD API

78958-6

Laboratory

Cathepsin A [Enzymatic activity/mass] in Leukocytes

Definition

Cathepsin A enzyme activity in leukocytes is measured as part of a diagnostic work-up for galactosialidosis. Patients with galactosialidosis will have decreased activity of the protective protein as well as decreased neuraminidase and β-galactosidase activity in leukocytes (and/or fibroblasts). Sequencing of the CTSA gene is performed for detection of disease-causing mutations.

LOINC 6-Axis Classification

Component

Cathepsin A

Property

CCnt

Time Aspect

Pt

System

WBC

Scale Type

Qn

Method Type

N/A

Details

Class

CHEM

Order/Observation

Both

Short Name

Cathepsin A WBC-cCnt

Display Name

Cathepsin A (WBC) [Catalytic activity/Mass]

Related Names

Catalytic ContentChemistryGalactosialidosisGalactosidaseLeukocytesLysosomal Protective ProteinPoint in timeQNTQuanQuantQuantitativeRandomWBCsWhite blood cells

Frequently Asked Questions

What is LOINC code 78958-6?

LOINC code 78958-6 identifies "Cathepsin A [Enzymatic activity/mass] in Leukocytes". Cathepsin A enzyme activity in leukocytes is measured as part of a diagnostic work-up for galactosialidosis. Patients with galactosialidosis will have decreased activity of the protective protein as well as decreased neuraminidase and β-galactosidase activity in leukocytes (and/or fibroblasts). Sequencing of the CTSA gene is performed for detection of disease-causing mutations.

What does 78958-6 measure?

This code measures Cathepsin A in WBC. It belongs to the CHEM class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.