78688-9
LaboratoryPlatelet aggregation [Units/volume] in Blood by adenosine diphosphate+prostaglandin E1 induced
Definition
Quantitative in vitro determination of platelet function in whole blood triggered by the addition of adenosine diphosphate (ADP) and prostaglandin E1 (PGE1). ADP induces platelet aggregation by two pathways mediated by the platelet receptors P2Y1 and P2Y12, respectively. The addition of PGE1 inhibits the P2Y1 activation pathway, which enables more specific evaluation of substances, such as clopidogrel, that affect platelet aggregation through the P2Y12 pathway. This term was created for, but not limited in use to, the Cobas Prostaglandin E1 Reagent used in conjunction with the ADPtest. The combination of the two is also known as ADPtest High Sensitivity (HS) assay.
LOINC 6-Axis Classification
Component
Platelet aggregation
Property
ACnc
Time Aspect
Pt
System
Bld
Scale Type
Qn
Method Type
Aggregometry.adenosine diphosphate+prostaglandin E1 induced
Details
Class
COAG
Order/Observation
Both
Short Name
PA Bld ADP+PGE1 induced-aCnc
Display Name
Platelet aggregation Qn (Bld)
Related Names
Frequently Asked Questions
What is LOINC code 78688-9?
LOINC code 78688-9 identifies "Platelet aggregation [Units/volume] in Blood by adenosine diphosphate+prostaglandin E1 induced". Quantitative in vitro determination of platelet function in whole blood triggered by the addition of adenosine diphosphate (ADP) and prostaglandin E1 (PGE1). ADP induces platelet aggregation by two pathways mediated by the platelet receptors P2Y1 and P2Y12, respectively. The addition of PGE1 inhibits the P2Y1 activation pathway, which enables more specific evaluation of substances, such as clopidogrel, that affect platelet aggregation through the P2Y12 pathway. This term was created for, but not limited in use to, the Cobas Prostaglandin E1 Reagent used in conjunction with the ADPtest. The combination of the two is also known as ADPtest High Sensitivity (HS) assay.
What does 78688-9 measure?
This code measures Platelet aggregation in Bld. It belongs to the COAG class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.