AutoICD API

78358-9

Laboratory

Acyl CoA dehydrogenases [Enzymatic activity/mass] in Fibroblast by [9,10-3H] palmitate substrate

Definition

Fatty acid oxidation in medium- or long-chain acyl CoA dehydrogenase deficiencies can be measured by quantifying the release of 3H2O from (9,10-3H) palmitate (this term) and myristate [LOINC: 78360-5] substrates added to cultured fibroblast. [PMID: 2109149] Fatty acid (i.e. palmitate or myristate) oxidation rates by fibroblasts are expressed as nanomole of 3H fatty acid (3H FA) oxidized per hour per milligram of cell protein (nmol 3H FA/h/mg protein).[PMID: 12840153]

LOINC 6-Axis Classification

Component

Acyl CoA dehydrogenases

Property

CCnt

Time Aspect

Pt

System

Fibroblasts

Scale Type

Qn

Method Type

[9,10-3H] palmitate substrate

Details

Class

CHEM

Order/Observation

Both

Short Name

ACADs Fib Palmitate-cCnt

Display Name

Acyl CoA dehydrogenases [9,10-3H] palmitate substrate (Fibroblast) [Catalytic activity/Mass]

Related Names

ACADsCatalytic ContentChemistryFibFibrPoint in timeQNTQuanQuantQuantitativeRandom

Frequently Asked Questions

What is LOINC code 78358-9?

LOINC code 78358-9 identifies "Acyl CoA dehydrogenases [Enzymatic activity/mass] in Fibroblast by [9,10-3H] palmitate substrate". Fatty acid oxidation in medium- or long-chain acyl CoA dehydrogenase deficiencies can be measured by quantifying the release of 3H2O from (9,10-3H) palmitate (this term) and myristate [LOINC: 78360-5] substrates added to cultured fibroblast. [PMID: 2109149] Fatty acid (i.e. palmitate or myristate) oxidation rates by fibroblasts are expressed as nanomole of 3H fatty acid (3H FA) oxidized per hour per milligram of cell protein (nmol 3H FA/h/mg protein).[PMID: 12840153]

What does 78358-9 measure?

This code measures Acyl CoA dehydrogenases in Fibroblasts. It belongs to the CHEM class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.