AutoICD API

77959-5

Laboratory

Yellow fever virus ns5 gene [Presence] in Cerebral spinal fluid by NAA with non-probe detection

Definition

This assay comprises qRT-PCR targeting the ns5 gene in the yellow fever backbone followed by melt curve analysis, which identifies DNA fragments with different nucleotide compositions based on their unique melting temperature. [PMID: 18501437] CSF testing is indicated for suspected adverse neurological reactions to the vaccine against yellow fever. Genome detection of CSF yellow fever vaccine in this context is considered diagnostic. In suspected patients, detection of antibodies against yellow fever in CSF should also be requested.

LOINC 6-Axis Classification

Component

Yellow fever virus ns5 gene

Property

PrThr

Time Aspect

Pt

System

CSF

Scale Type

Ord

Method Type

Non-probe.amp.tar

Details

Class

MICRO

Order/Observation

Both

Short Name

YFV ns5 gene CSF Ql NAA+n-prb

Display Name

Yellow fever virus ns5 gene NAA+non-probe Ql (CSF)

Related Names

3 Self-Sustaining Sequence Replication3SR SRAmerican plagueAmplifAmplificationAmplifiedCerebral spinal fluidCerebrospinal FlDNA NUCLEIC ACID PROBEDNA probeIDInfectious DiseaseInfectiousDiseaseLATLCRLigase chain reactionLigation-activated transcriptionMicrobiologyNAA+n-prbNAA+probeNAATNASBANeuroNeurologyNucleic acid sequence based analysisOrdinalPCRPoint in timePolymerase chain reactionPRProbe ampProbe with ampificationProbe with target amplificationQBRQLQualQualitativeRandomScreenSDASpinal FlSpinal FldSpinal FluSpinal FluidStrand Displacement AmplificationTMATranscription mediated amplificationyellow jackYFVYFV ns5 gene

Frequently Asked Questions

What is LOINC code 77959-5?

LOINC code 77959-5 identifies "Yellow fever virus ns5 gene [Presence] in Cerebral spinal fluid by NAA with non-probe detection". This assay comprises qRT-PCR targeting the ns5 gene in the yellow fever backbone followed by melt curve analysis, which identifies DNA fragments with different nucleotide compositions based on their unique melting temperature. [PMID: 18501437] CSF testing is indicated for suspected adverse neurological reactions to the vaccine against yellow fever. Genome detection of CSF yellow fever vaccine in this context is considered diagnostic. In suspected patients, detection of antibodies against yellow fever in CSF should also be requested.

What does 77959-5 measure?

This code measures Yellow fever virus ns5 gene in CSF. It belongs to the MICRO class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.