77622-9
LaboratoryNatriuretic peptide.B prohormone N-Terminal [Mass/volume] in Peritoneal dialysis fluid by Immunoassay
Definition
Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are significantly elevated in patients with heart failure because tension or stretching of the cardiac wall, such as occurs with heart failure, stimulates the synthesis of natriuretic peptides. Elevated levels are associated with adverse outcomes in both hemodialysis (HD) and peritoneal dialysis (PD) patients and are attributable to both ventricular dysfunction and decreased renal clearance. Peritoneal dialysate and plasma NT-proBNP levels are linearly related. [PMID: 21427249] This term was created for, but is not restricted in use to, the Elecsys proBNP II assay, which contains two monoclonal antibodies that recognize epitopes located in the N-terminal part (1-76) of proBNP (1-108).
LOINC 6-Axis Classification
Component
Natriuretic peptide.B prohormone N-Terminal
Property
MCnc
Time Aspect
Pt
System
Dial fld prt
Scale Type
Qn
Method Type
IA
Details
Class
CHEM
Order/Observation
Both
Short Name
NT-proBNP DiafP IA-mCnc
Display Name
Natriuretic peptide.B prohormone N-Terminal IA (Perit dial fld) [Mass/Vol]
Related Names
Frequently Asked Questions
What is LOINC code 77622-9?
LOINC code 77622-9 identifies "Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Peritoneal dialysis fluid by Immunoassay". Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are significantly elevated in patients with heart failure because tension or stretching of the cardiac wall, such as occurs with heart failure, stimulates the synthesis of natriuretic peptides. Elevated levels are associated with adverse outcomes in both hemodialysis (HD) and peritoneal dialysis (PD) patients and are attributable to both ventricular dysfunction and decreased renal clearance. Peritoneal dialysate and plasma NT-proBNP levels are linearly related. [PMID: 21427249] This term was created for, but is not restricted in use to, the Elecsys proBNP II assay, which contains two monoclonal antibodies that recognize epitopes located in the N-terminal part (1-76) of proBNP (1-108).
What does 77622-9 measure?
This code measures Natriuretic peptide.B prohormone N-Terminal in Dial fld prt. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.