77367-1

LOINC code 77367-1 identifies "Cholinesterase [Enzymatic activity/volume] in Serum or Plasma by calculation --Dibucaine". People with genetic variants or acquired deficiencies of plasma cholinesterase that result in lower enzymatic activity can have a very difficult time recovering from surgery. To identify these patients, tests using various inhibitory agents are performed. The most common inhibitors are fluoride and dibucaine. The degree to which the agent inhibits the enzyme (fluoride number or dibucaine number) can be used to predict neuromuscular recovery after surgery. Other inhibitors include chloride, RO 020683, and scoline. This term was created for, but not limited in use to, the Roche cobas Cholinesterase / Dibucaine Gen.2 test kit.

This code measures Cholinesterase^dibucaine in Ser/Plas. It belongs to the CHEM class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.