77217-8

LOINC code 77217-8 identifies "Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA and IgG and IgM panel - Serum by Immunoassay". Sjogren's disease is an autoimmune disease associated with kidney and lung disease as well as disorders of the salivary and lacrimal glands, which lead to problems with dry eyes and mouth. Sjogren's syndrome is associated with isolated salivary and lacrimal gland dysfunction and may be associated with other autoimmune disorders, such as systemic lupus erythematosus. Antibodies to salivary gland protein 1 (SP-1), carbonic anhydrase 6 (CA6) and parotid secretory protein (PSP) may be useful markers for identifying patients with Sjogren's disease or Sjogren's syndrome early in the course of disease and for those who have significant symptoms but are anti-Ro and anti-La antibody negative, which are two of the antibodies that are typically used to diagnose Sjogren's. Antibodies to SP-1, CA6 and PSP rarely occur in healthy controls or patients with other autoimmune disorders who do not have eye and mouth symptoms. [PMID: 23123440] This term was created for, but is not limited in use to, the IMMCO Diagnostics' early Sjogren's syndrome antibody profile, which includes terms for IgA, IgG and IgM antibodies to SP-1, CA6 and PSP.

This code measures Salivary gland protein 1 & Carbonic anhydrase 6 & Parotid secretory protein Ab.IgA & IgG & IgM panel in Ser. It belongs to the PANEL.SERO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.