77175-8

LOINC code 77175-8 identifies "Coxiella burnetii phase 1 and 2 IgG and IgM panel - Serum". This panel combines assays for phase 1 and 2, IgG and IgM antibody testing, for diagnosing past and present Q fever infections caused by Coxiella burnetii. Coxiella burnetii is a species of intracellular, pathogenic bacteria, and is the causative agent of Q fever. The genus Coxiella is morphologically similar to the rickettsia, but with a variety of genetic and physiological differences. C. burnetii are small Gram negative bacteria with two growth phases, as well as a spore form which lies idle in soil. It can survive standard disinfectants, and is resistant to many other environmental changes. Pathogenesis:The ID50 (the dose need to infect 50% of experimental subjects) is one via inhalation i.e. inhalation of one organism will yield disease in 50% of the population. Disease occurs in two states: An acute state presents with headaches, chills, and respiratory symptoms, and an insidious chronic stage. While most infections clear up spontaneously, treatment with tetracycline appears to reduce the symptomatic duration and reduce the likelihood of chronic infection.

This code measures Coxiella burnetii phase 1 & 2 Ab.IgG & IgM panel in Ser. It belongs to the PANEL.MICRO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.