76498-5
LaboratoryCervical cells.overexpressing HPV E6+E7 mRNA/cervical cells by Flow cytometry (FC)
Definition
Detects E6/E7 mRNA in sufficient quantity to demonstrate integration and expression in ectocervical cells in cervical specimens in which high-risk HPV types have been previously been detected. (This test should only be performed on specimens found to be positive by other high-risk HPV detection methods.) Detection may identify infection more likely to progress to disease as the detection of E6/E7 is not only a sign of virus within the cell, but also evidence of viral activity and thus may help discriminate the presence of CIN2+ disease. This term was created for, but not limited in use to, the LabCorp QuantaSURE mRNA based test which measures the quantity of E6/E7 mRNA per cell and then calculates the percentage of cells that are overexpressing E6/E7 mRNA.
LOINC 6-Axis Classification
Component
Cervical cells.overexpressing HPV E6+E7 mRNA/cervical cells
Property
NFr
Time Aspect
Pt
System
Cvx
Scale Type
Qn
Method Type
Flow cytometry
Details
Class
MICRO
Order/Observation
Both
Short Name
Cvx cel HPVE6+E7mRNA/Cvx cel FC-NFr
Display Name
Cervical cells.overexpressing HPV E6+E7 mRNA/cervical cells FC (Cvx)
Related Names
Frequently Asked Questions
What is LOINC code 76498-5?
LOINC code 76498-5 identifies "Cervical cells.overexpressing HPV E6+E7 mRNA/cervical cells by Flow cytometry (FC)". Detects E6/E7 mRNA in sufficient quantity to demonstrate integration and expression in ectocervical cells in cervical specimens in which high-risk HPV types have been previously been detected. (This test should only be performed on specimens found to be positive by other high-risk HPV detection methods.) Detection may identify infection more likely to progress to disease as the detection of E6/E7 is not only a sign of virus within the cell, but also evidence of viral activity and thus may help discriminate the presence of CIN2+ disease. This term was created for, but not limited in use to, the LabCorp QuantaSURE mRNA based test which measures the quantity of E6/E7 mRNA per cell and then calculates the percentage of cells that are overexpressing E6/E7 mRNA.
What does 76498-5 measure?
This code measures Cervical cells.overexpressing HPV E6+E7 mRNA/cervical cells in Cvx. It belongs to the MICRO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.