76479-5
LaboratoryAcetylcholinesterase [Interpretation] in Amniotic fluid Narrative
Definition
An interpretation of the acetylcholinesterase (AChE) in amniotic fluid testing result which is used as an aid to diagnose open neural tube defect (NDT) and ventral wall defects. The two most common neural tube defects are spina bifida and anencephaly. When an NTD is suspected based upon maternal serum alpha-fetoprotein (AFP) screening results, or diagnosed via ultrasound, detection of acetylcholinesterase (AChE) in amniotic fluid is a useful diagnostic tool as normal amniotic fluid does not contain AChE, unless from the fetus as a result of an open NTD. The patient's gestational age must be at least 13 weeks (second trimester) for accurate AChE detection. Optimal gestational age is 14 to 18 weeks. If acetylcholinesterase is present genetic consultation and high-resolution ultrasound may be suggested.
LOINC 6-Axis Classification
Component
Acetylcholinesterase
Property
Imp
Time Aspect
Pt
System
Amnio fld
Scale Type
Nar
Method Type
N/A
Details
Class
CHEM
Order/Observation
Observation
Short Name
AChE Amn-Imp
Display Name
Acetylcholinesterase Nar (Amn fld) [Interp]
Related Names
Frequently Asked Questions
What is LOINC code 76479-5?
LOINC code 76479-5 identifies "Acetylcholinesterase [Interpretation] in Amniotic fluid Narrative". An interpretation of the acetylcholinesterase (AChE) in amniotic fluid testing result which is used as an aid to diagnose open neural tube defect (NDT) and ventral wall defects. The two most common neural tube defects are spina bifida and anencephaly. When an NTD is suspected based upon maternal serum alpha-fetoprotein (AFP) screening results, or diagnosed via ultrasound, detection of acetylcholinesterase (AChE) in amniotic fluid is a useful diagnostic tool as normal amniotic fluid does not contain AChE, unless from the fetus as a result of an open NTD. The patient's gestational age must be at least 13 weeks (second trimester) for accurate AChE detection. Optimal gestational age is 14 to 18 weeks. If acetylcholinesterase is present genetic consultation and high-resolution ultrasound may be suggested.
What does 76479-5 measure?
This code measures Acetylcholinesterase in Amnio fld. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.