AutoICD API

76063-7

Laboratory

MSH2 gene+MLH1 gene+MSH6 gene mutation analysis limited to known familial mutations in Blood or Tissue by Molecular genetics method

Definition

This term is used for carrier or diagnostic testing for at-risk or presymptomatic relatives of an affected individual who has a previously identified known genetic mutation within the MLH1, MSH2 or MSH6 genes. Mutations in these genes cause hereditary nonpolyposis colorectal cancer (HNPCC). Mutation analysis only includes testing for the known familial mutation.

LOINC 6-Axis Classification

Component

MSH2 gene+MLH1 gene+MSH6 gene mutation analysis limited to known familial mutations

Property

Find

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Doc

Method Type

Molgen

Details

Class

MOLPATH.MUT

Order/Observation

Both

Short Name

MSH2+MLH1+MSH6 gene Fam Mut Anl Bld/T

Display Name

MSH2 gene+MLH1 gene+MSH6 gene familial mut analysis Molgen Doc (Bld/Tiss)

Related Names

BAT-26BloodCOCA1COCA2Colon cancer nonpolyposis type 1DocumentFam Mut AnlFCC1FCC2FindingFindingsG/T mismatch-binding protein geneGeneticsGTBPGTMBPHereditary Nonpolyposis Colorectal CancerHeredityHeritablehMLH1HNPCCHNPCC1HNPCC2HNPCC5HSAPInheritedLCFS2LMTEDLTDLynch syndromeMGC5172Molecular geneticsMolecular pathologyMOLPATHMOLPATH.MUTATIONSMSH2+MLH1 geneMSH2+MLH1+MSH6 geneMutMutationMutationsmutL homolog 1MutL homolog 1, colon cancer, nonpolyposis type 2MutsmutS homolog 2mutS homolog 6p160PCRPoint in timeRandomTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 76063-7?

LOINC code 76063-7 identifies "MSH2 gene+MLH1 gene+MSH6 gene mutation analysis limited to known familial mutations in Blood or Tissue by Molecular genetics method". This term is used for carrier or diagnostic testing for at-risk or presymptomatic relatives of an affected individual who has a previously identified known genetic mutation within the MLH1, MSH2 or MSH6 genes. Mutations in these genes cause hereditary nonpolyposis colorectal cancer (HNPCC). Mutation analysis only includes testing for the known familial mutation.

What does 76063-7 measure?

This code measures MSH2 gene+MLH1 gene+MSH6 gene mutation analysis limited to known familial mutations in Bld/Tiss. It belongs to the MOLPATH.MUT class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.