75217-0
LaboratoryBiotinidase [Enzymatic activity/volume] in DBS
Definition
Biotinidase is a marker for biotinidase deficiency, which is one of the core conditions on the HHS Secretary's Recommended Uniform Screening Panel for newborn screening. The submitter's lab uses Astoria-Pacific's SPOTCHECK analyzer to measure biotinidase, which is reported in ERUs (enzyme response units). ERU units are defined as follows: "One ERU is equal to one micromole of PABA (product) produced from Biotin-PAB (substrate) per 100 mL per 90 minutes in the extract from a dried blood spot."
LOINC 6-Axis Classification
Component
Biotinidase
Property
CCnc
Time Aspect
Pt
System
Bld.dot
Scale Type
Qn
Method Type
N/A
Details
Class
CHEM
Order/Observation
Both
Short Name
Biotinidase DBS-cCnc
Display Name
Biotinidase (DBS) [Catalytic activity/Vol]
Related Names
Frequently Asked Questions
What is LOINC code 75217-0?
LOINC code 75217-0 identifies "Biotinidase [Enzymatic activity/volume] in DBS". Biotinidase is a marker for biotinidase deficiency, which is one of the core conditions on the HHS Secretary's Recommended Uniform Screening Panel for newborn screening. The submitter's lab uses Astoria-Pacific's SPOTCHECK analyzer to measure biotinidase, which is reported in ERUs (enzyme response units). ERU units are defined as follows: "One ERU is equal to one micromole of PABA (product) produced from Biotin-PAB (substrate) per 100 mL per 90 minutes in the extract from a dried blood spot."
What does 75217-0 measure?
This code measures Biotinidase in Bld.dot. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.