74635-4

LOINC code 74635-4 identifies "Bacterial vaginosis DNA panel - Vaginal fluid by NAA with probe detection". Real-Time Polymerase Chain Reaction (RT-PCR) is performed on vaginal specimen to assess for bacterial vaginosis (BV). Regions of the 16S ribosomal RNA genes of normal peroxidase-producing Lactobacillus species (L acidophilus, L crispatus, and L jensenii) and BV-associated bacteria (G vaginalis, A vaginae, and Megasphaera spp) are targeted for detection. This panel was created for, but not limited in use to, the SureSwab(R) Bacterial Vaginosis DNA assay. Concentrations of Lactobacilli are collectively reported under the term "Lactobacillus spp." These species are among the peroxide producing Lactobacilli thought to be protective against bacterial vaginosis. In the absence of peroxide producing Lactobacilli, Atopobium vaginae, Megasphaera spp., and Gardnerella (>6.0 log cells/mL) have been associated with BV.

This code measures Bacterial vaginosis DNA panel in Vag. It belongs to the PANEL.MICRO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.