AutoICD API

74007-6

Laboratory

CYP3A4 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method

Definition

CYP3A4 gene mutation analysis for targeted polymorphisms (SNPs) is performed to determine a patient's allellic genotype and overall drug metabolism phenotype (ultrarapid, extenisive, intermediate, or poor metabolizer). This term is used to report the patient's allelic genotype, drug metabolism phenotype and overall interpretation in a single narrative report. The submitter's lab currently (as of 2013) tests for the following CYP3A4 alleles: *1B, *1G, *3, *4, *5, *6, *10, *12, *17, *18, *20 and *22. Selection is based on current literature. For a complete list of alleles and more information on CYP3A4, see http://www.cypalleles.ki.se/cyp3a4.htm.

LOINC 6-Axis Classification

Component

CYP3A4 gene targeted mutation analysis

Property

Find

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Doc

Method Type

Molgen

Details

Class

MOLPATH.PHARMG

Order/Observation

Both

Short Name

CYP3A4 Mut Anl Bld/T

Display Name

CYP3A4 gene targeted mutation analysis Molgen Doc (Bld/Tiss)

Related Names

BloodCP33CP34CYP3ACYP3A3CYPIIIA3CYPIIIA4cytochrome P450, family 3, subfamily A, polypeptide 4DocumentFindingFindingsGeneticsHeredityHeritableHLPInheritedMolecular geneticsMolecular pathologyMOLPATHMOLPATH.PHARMGMutMut AnlMutationsNF-25P450C3P450PCN1PCRPoint in timeRandomTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 74007-6?

LOINC code 74007-6 identifies "CYP3A4 gene targeted mutation analysis in Blood or Tissue by Molecular genetics method". CYP3A4 gene mutation analysis for targeted polymorphisms (SNPs) is performed to determine a patient's allellic genotype and overall drug metabolism phenotype (ultrarapid, extenisive, intermediate, or poor metabolizer). This term is used to report the patient's allelic genotype, drug metabolism phenotype and overall interpretation in a single narrative report. The submitter's lab currently (as of 2013) tests for the following CYP3A4 alleles: *1B, *1G, *3, *4, *5, *6, *10, *12, *17, *18, *20 and *22. Selection is based on current literature. For a complete list of alleles and more information on CYP3A4, see http://www.cypalleles.ki.se/cyp3a4.htm.

What does 74007-6 measure?

This code measures CYP3A4 gene targeted mutation analysis in Bld/Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.