AutoICD API

72882-4

Laboratory

CYP2B6 gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

Definition

A patient's genotype for the CYP2B6 gene is typically reported as *A/*B where A is the allele from one chromosome and B is the allele from the other chromosome. The genotype is determined by the analysis of specific single nucleotide polymorphisms (SNPs) within the gene by various molecular techniques, including PCR and microarray. A number of variants within this gene are associated with altered drug metabolism have been described, including *8 (415A>G), *9 (516G>T), *16 (983T>C), and *5 (1459C>T). In some cases, SNP results are analyzed by bioinformatics computer software to determine a patient's overall genotype.

LOINC 6-Axis Classification

Component

CYP2B6 gene allele

Property

Geno

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Nom

Method Type

Molgen

Details

Class

MOLPATH.PHARMG

Order/Observation

Both

Short Name

CYP2B6 allele Geno Bld/T

Display Name

CYP2B6 gene allele genotype Molgen (Bld/Tiss)

Related Names

BloodCPB6CYP2BCYP2B6 alleleCYP2B7CYP2B7PCYPIIB6cytochrome P450, family 2, subfamily B, polypeptide 6EFVMGeneticsHeredityHeritableIIB1InheritedMolecular geneticsMolecular pathologyMOLPATHMOLPATH.PHARMGNominalP450PCRPoint in timeRandomTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 72882-4?

LOINC code 72882-4 identifies "CYP2B6 gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal". A patient's genotype for the CYP2B6 gene is typically reported as *A/*B where A is the allele from one chromosome and B is the allele from the other chromosome. The genotype is determined by the analysis of specific single nucleotide polymorphisms (SNPs) within the gene by various molecular techniques, including PCR and microarray. A number of variants within this gene are associated with altered drug metabolism have been described, including *8 (415A>G), *9 (516G>T), *16 (983T>C), and *5 (1459C>T). In some cases, SNP results are analyzed by bioinformatics computer software to determine a patient's overall genotype.

What does 72882-4 measure?

This code measures CYP2B6 gene allele in Bld/Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.