AutoICD API

72160-5

Laboratory

Holo-transcobalamin II [Moles/volume] in Serum

Definition

The fraction of vitamin B12 bound to transcobalamin II (TC-II), normally <30% of the total, is considered the "active" fraction available to cells. There have been claims in the literature that measurement of specifically the "active" fraction is an earlier indicator of deficiency, although as of 2011 this claim is reported to be controversial (Am J Clin Nutr. 2011 Jul;94(1):348S-358S. Epub 2011 May 18).

LOINC 6-Axis Classification

Component

Holo-transcobalamin II

Property

SCnc

Time Aspect

Pt

System

Ser

Scale Type

Qn

Method Type

N/A

Details

Class

CHEM

Order/Observation

Both

Short Name

Holo-TC-II Ser-sCnc

Display Name

Holo-transcobalamin II (S) [Moles/Vol]

Related Names

2Active B12Active vitamin B12ChemistryCobalaminhaptocorrinholo-haptocorrinholo-TCHolo-TC-IIHolotranscobalaminLevelPoint in timeQNTQuanQuantQuantitativeRandomSerumSRSubstance concentrationTCTC-2TCIITC-IITranscobalaminTranscobalamin 2Vit B12Vitamin B12

Frequently Asked Questions

What is LOINC code 72160-5?

LOINC code 72160-5 identifies "Holo-transcobalamin II [Moles/volume] in Serum". The fraction of vitamin B12 bound to transcobalamin II (TC-II), normally <30% of the total, is considered the "active" fraction available to cells. There have been claims in the literature that measurement of specifically the "active" fraction is an earlier indicator of deficiency, although as of 2011 this claim is reported to be controversial (Am J Clin Nutr. 2011 Jul;94(1):348S-358S. Epub 2011 May 18).

What does 72160-5 measure?

This code measures Holo-transcobalamin II in Ser. It belongs to the CHEM class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.