69358-0
LaboratoryHPV E6+E7 mRNA cells/cells [Presence] in Cervix by Flow cytometry (FC)
Definition
This term was created for an assay that identifies cervical cells containing HPV E6 and E7 polycistronic mRNA using in situ hybridization with oligonucleotides specific for the mRNA transcripts. The cells remain intact, and following fixation and permeabilization, the probes enter the cells. The flow cytometer measures two things: 1. Quantification of E6 and E7 mRNA in each cell and 2. The percentage of cells over-expressing E6 and E7 mRNA. The test does not report the percentage quantity but an ordinal (positive, negative, indeterminant) based on the reported percentage. This test is similar to LOINC 69002-4, which is a target amplification nucleic acid probe test to detect E6+E7 mRNA.
LOINC 6-Axis Classification
Component
Cells.HPV E6+E7 mRNA/cells
Property
PrThr
Time Aspect
Pt
System
Cvx
Scale Type
Ord
Method Type
Flow cytometry
Details
Class
MICRO
Order/Observation
Both
Short Name
HPV E6+E7 mRNA cells/cells Cvx Ql FC
Display Name
HPV E6+E7 mRNA cells/Cells FC Ql (Cvx)
Related Names
Frequently Asked Questions
What is LOINC code 69358-0?
LOINC code 69358-0 identifies "HPV E6+E7 mRNA cells/cells [Presence] in Cervix by Flow cytometry (FC)". This term was created for an assay that identifies cervical cells containing HPV E6 and E7 polycistronic mRNA using in situ hybridization with oligonucleotides specific for the mRNA transcripts. The cells remain intact, and following fixation and permeabilization, the probes enter the cells. The flow cytometer measures two things: 1. Quantification of E6 and E7 mRNA in each cell and 2. The percentage of cells over-expressing E6 and E7 mRNA. The test does not report the percentage quantity but an ordinal (positive, negative, indeterminant) based on the reported percentage. This test is similar to LOINC 69002-4, which is a target amplification nucleic acid probe test to detect E6+E7 mRNA.
What does 69358-0 measure?
This code measures Cells.HPV E6+E7 mRNA/cells in Cvx. It belongs to the MICRO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.