AutoICD API

53717-5

Laboratory

PCA-1 Ab [Titer] in Serum

Definition

PCA-1 antibody is rarely found in patients with neurologic diseases without breast or gynecologic cancer. Conversely, it is rarely found in patients with breast or gynecologic cancer without neurologic dysfunction. Paraneoplastic cerebellar degeneration is associated with breast or gynecological (ovarian, fallopian, endometrial) tumors, and less commonly with lung (SCLC -small cell lung cancer) or Hodgkin lymphoma. More than 50% of seropositive patients present with subacute cerbellar ataxia and approximately 5% with sensorimotor or motor neuropathy. Information from http://www.clinlabnavigator.com accessed 2008 14 02.

LOINC 6-Axis Classification

Component

Purkinje cell cytoplasmic type 1 Ab

Property

Titr

Time Aspect

Pt

System

Ser

Scale Type

SemiQn

Method Type

N/A

Details

Class

SERO

Order/Observation

Both

Short Name

PCA-1 Ab Titr Ser

Display Name

PCA-1 Ab (S) [Titer]

Related Names

ABSAbyAntbyAntiAntibodiesAntibodyAnti-Yo-Associated Paraneoplastic Cerebellar DegenerationAutoantibodiesAutoantibodyCytoplCytoplasDilution factorDilution Factor (Titer)iParaneoplastic syndromePCA1PCA-1PCCA-1Point in timePurkinje cell cytoplasmic antibodyPurkinje cellsRandomSerologySerumSmQnSRTiterTiteredTitreTtrYo Ab

Frequently Asked Questions

What is LOINC code 53717-5?

LOINC code 53717-5 identifies "PCA-1 Ab [Titer] in Serum". PCA-1 antibody is rarely found in patients with neurologic diseases without breast or gynecologic cancer. Conversely, it is rarely found in patients with breast or gynecologic cancer without neurologic dysfunction. Paraneoplastic cerebellar degeneration is associated with breast or gynecological (ovarian, fallopian, endometrial) tumors, and less commonly with lung (SCLC -small cell lung cancer) or Hodgkin lymphoma. More than 50% of seropositive patients present with subacute cerbellar ataxia and approximately 5% with sensorimotor or motor neuropathy. Information from http://www.clinlabnavigator.com accessed 2008 14 02.

What does 53717-5 measure?

This code measures Purkinje cell cytoplasmic type 1 Ab in Ser. It belongs to the SERO class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.