AutoICD API

53040-2

Laboratory

Genetic variation's effect on drug metabolism

Definition

Predicted phenotype for drug efficacy. A single marker interpretation value known to allow (responsive) or prevent (resistant) the drug to perform. Prior to the LOINC release 2.56 (June 2016), the answer list was updated per the recommendations of the Clinical Pharmacogenetics Implementation Consortium (CPIC). The previous answer list number was LL609-9, and three of the answer strings and LA codes are the same in the new list (ultrarapid metabolizer, intermediate metabolizer, and poor metabolizer). In the new answer list, the extensive metabolizer answer (LA10316-0) from LL609-9 has been replaced with two new answers (rapid metabolizer, normal metabolizer). LA10316-0 is still a valid LA code for the "extensive metabolizer" answer string.

LOINC 6-Axis Classification

Component

Drug metabolism sequence variation interpretation

Property

Imp

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Ord

Method Type

Molgen

Details

Class

HL7.GENETICS

Order/Observation

Observation

Short Name

Drug metab seq var interp-Imp

Display Name

Drug metabolism sequence variation interpretation Molgen Ql (Bld/Tiss) [Interp]

Related Names

BloodDrug metab seq var interpDrugsGeneticGeneticsGenomicHL7.GENETICSImpressionImpression/interpretation of studyImpressionsInterpInterpretInterpretationInterptIntrpMolecular geneticsMOLPATH.GENERALOrdinalPCRPoint in timeQLQualQualitativeRandomScreenTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 53040-2?

LOINC code 53040-2 identifies "Genetic variation's effect on drug metabolism". Predicted phenotype for drug efficacy. A single marker interpretation value known to allow (responsive) or prevent (resistant) the drug to perform. Prior to the LOINC release 2.56 (June 2016), the answer list was updated per the recommendations of the Clinical Pharmacogenetics Implementation Consortium (CPIC). The previous answer list number was LL609-9, and three of the answer strings and LA codes are the same in the new list (ultrarapid metabolizer, intermediate metabolizer, and poor metabolizer). In the new answer list, the extensive metabolizer answer (LA10316-0) from LL609-9 has been replaced with two new answers (rapid metabolizer, normal metabolizer). LA10316-0 is still a valid LA code for the "extensive metabolizer" answer string.

What does 53040-2 measure?

This code measures Drug metabolism sequence variation interpretation in Bld/Tiss. It belongs to the HL7.GENETICS class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.