106939-2
LaboratoryAmyloid probability score in Plasma by Calculation
Definition
The term repersents The PrecivityAD2™ test. This test is an analytically and clinically validated blood test designed to assist healthcare providers in diagnosing Alzheimer's disease (AD) in patients with mild cognitive impairment or dementia. It quantifies specific plasma amyloid beta and tau peptides using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to calculate the Aβ42/40 and p-tau217/np-tau217 ratios. These ratios are combined in a proprietary algorithm to produce the Amyloid Probability Score 2 (APS2), a numerical value from 0-100 that indicates the likelihood of brain amyloid plaques. By providing a non-invasive alternative to PET scans, the PrecivityAD2™ test enhances diagnostic accuracy while mitigating the effects of confounding factors.
LOINC 6-Axis Classification
Component
Amyloid plaques probability score
Property
Score
Time Aspect
Pt
System
Plas
Scale Type
Nom
Method Type
Calculation
Details
Class
SERO
Order/Observation
Both
Short Name
Amyloid prob score Plas Calc
Display Name
Amyloid plaques probability score Calc Nom (P)
Related Names
Frequently Asked Questions
What is LOINC code 106939-2?
LOINC code 106939-2 identifies "Amyloid probability score in Plasma by Calculation". The term repersents The PrecivityAD2™ test. This test is an analytically and clinically validated blood test designed to assist healthcare providers in diagnosing Alzheimer's disease (AD) in patients with mild cognitive impairment or dementia. It quantifies specific plasma amyloid beta and tau peptides using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to calculate the Aβ42/40 and p-tau217/np-tau217 ratios. These ratios are combined in a proprietary algorithm to produce the Amyloid Probability Score 2 (APS2), a numerical value from 0-100 that indicates the likelihood of brain amyloid plaques. By providing a non-invasive alternative to PET scans, the PrecivityAD2™ test enhances diagnostic accuracy while mitigating the effects of confounding factors.
What does 106939-2 measure?
This code measures Amyloid plaques probability score in Plas. It belongs to the SERO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.