102036-1

LOINC code 102036-1 identifies "Abnormal Prion Protein [Interpretation] in Cerebral spinal fluid Document by RT-QuIC". Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and other mammals. TSEs are protein misfolding diseases that involve the accumulation of an abnormally aggregated form of the normal host prion protein (PrP). They are unique among protein misfolding disorders in that they are transmissible and have different strains of infectious agents that are associated with unique phenotypes in vivo. https://pubmed.ncbi.nlm.nih.gov/19157856/#:~:text=Abstract,host%20prion%20protein%20(PrP).

This code measures Prion protein.abnormal in CSF. It belongs to the MICRO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.