Chapter 2: Neoplasms
ICD-10-CM codes C00-D49
Includes all codes for cancer (malignant neoplasms), benign tumors, carcinoma in situ, and neoplasms of uncertain behavior. Common codes include breast cancer (C50), lung cancer (C34), prostate cancer (C61), and colon cancer (C18). This chapter is critical for oncology billing and cancer registry reporting.
C00-C14
Malignant Neoplasms of Lip, Oral Cavity and Pharynx
C00Malignant neoplasm of lip
C01Malignant neoplasm of base of tongue
C02Malignant neoplasm of other and unspecified parts of tongue
C03Malignant neoplasm of gum
C04Malignant neoplasm of floor of mouth
C05Malignant neoplasm of palate
C06Malignant neoplasm of other and unspecified parts of mouth
C07Malignant neoplasm of parotid gland
C08Malignant neoplasm of other and unsp major salivary glands
C09Malignant neoplasm of tonsil
C10Malignant neoplasm of oropharynx
C11Malignant neoplasm of nasopharynx
C12Malignant neoplasm of pyriform sinus
C13Malignant neoplasm of hypopharynx
C14Malig neoplasm of sites in the lip, oral cavity and pharynx
C15-C26
Malignant Neoplasms of Digestive Organs
C15Malignant neoplasm of esophagus
C16Malignant neoplasm of stomach
C17Malignant neoplasm of small intestine
C18Malignant neoplasm of colon
C19Malignant neoplasm of rectosigmoid junction
C20Malignant neoplasm of rectum
C21Malignant neoplasm of anus and anal canal
C22Malignant neoplasm of liver and intrahepatic bile ducts
C23Malignant neoplasm of gallbladder
C24Malignant neoplasm of other and unsp parts of biliary tract
C25Malignant neoplasm of pancreas
C26Malignant neoplasm of other and ill-defined digestive organs
C30-C39
Malignant Neoplasms of Respiratory and Intrathoracic Organs
C30Malignant neoplasm of nasal cavity and middle ear
C31Malignant neoplasm of accessory sinuses
C32Malignant neoplasm of larynx
C33Malignant neoplasm of trachea
C34Malignant neoplasm of bronchus and lung
C37Malignant neoplasm of thymus
C38Malignant neoplasm of heart, mediastinum and pleura
C39Malig neoplm of sites in the resp sys and intrathorac organs
C40-C41
Malignant Neoplasms of Bone and Articular Cartilage
C43-C44
Melanoma and Other Malignant Neoplasms of Skin
C45-C49
Malignant Neoplasms of Mesothelial and Soft Tissue
C50-C50
Malignant Neoplasms of Breast
C51-C58
Malignant Neoplasms of Female Genital Organs
C51Malignant neoplasm of vulva
C52Malignant neoplasm of vagina
C53Malignant neoplasm of cervix uteri
C54Malignant neoplasm of corpus uteri
C55Malignant neoplasm of uterus, part unspecified
C56Malignant neoplasm of ovary
C57Malignant neoplasm of other and unsp female genital organs
C58Malignant neoplasm of placenta
C60-C63
Malignant Neoplasms of Male Genital Organs
C64-C68
Malignant Neoplasms of Urinary Tract
C69-C72
Malignant Neoplasms of Eye, Brain and Other Parts of CNS
C73-C75
Malignant Neoplasms of Thyroid and Other Endocrine Glands
C76-C80
Malignant Neoplasms of Ill-Defined, Other Secondary and Unspecified Sites
C76Malignant neoplasm of other and ill-defined sites
C77Secondary and unspecified malignant neoplasm of lymph nodes
C78Secondary malignant neoplasm of resp and digestive organs
C79Secondary malignant neoplasm of other and unspecified sites
C7AMalignant neuroendocrine tumors
C7BSecondary neuroendocrine tumors
C80Malignant neoplasm without specification of site
C81-C96
Malignant Neoplasms of Lymphoid, Hematopoietic and Related Tissue
C81Hodgkin lymphoma
C82Follicular lymphoma
C83Non-follicular lymphoma
C84Mature T/NK-cell lymphomas
C85Oth and unspecified types of non-Hodgkin lymphoma
C86Other specified types of T/NK-cell lymphoma
C88Malig immunoproliferative dis and certain oth B-cell lymph
C90Multiple myeloma and malignant plasma cell neoplasms
C91Lymphoid leukemia
C92Myeloid leukemia
C93Monocytic leukemia
C94Other leukemias of specified cell type
C95Leukemia of unspecified cell type
C96Oth & unsp malig neoplm of lymphoid, hematpoetc and rel tiss
D00-D09
In Situ Neoplasms
D00Carcinoma in situ of oral cavity, esophagus and stomach
D01Carcinoma in situ of other and unspecified digestive organs
D02Carcinoma in situ of middle ear and respiratory system
D03Melanoma in situ
D04Carcinoma in situ of skin
D05Carcinoma in situ of breast
D06Carcinoma in situ of cervix uteri
D07Carcinoma in situ of other and unspecified genital organs
D09Carcinoma in situ of other and unspecified sites
D10-D36
Benign Neoplasms, Except Benign Neuroendocrine Tumors
D10Benign neoplasm of mouth and pharynx
D11Benign neoplasm of major salivary glands
D12Benign neoplasm of colon, rectum, anus and anal canal
D13Benign neoplasm of and ill-defined parts of digestive system
D14Benign neoplasm of middle ear and respiratory system
D15Benign neoplasm of other and unsp intrathoracic organs
D16Benign neoplasm of bone and articular cartilage
D17Benign lipomatous neoplasm
D18Hemangioma and lymphangioma, any site
D19Benign neoplasm of mesothelial tissue
D20Benign neoplm of soft tissue of retroperiton and peritoneum
D21Other benign neoplasms of connective and other soft tissue
D22Melanocytic nevi
D23Other benign neoplasms of skin
D24Benign neoplasm of breast
D25Leiomyoma of uterus
D26Other benign neoplasms of uterus
D27Benign neoplasm of ovary
D28Benign neoplasm of other and unsp female genital organs
D29Benign neoplasm of male genital organs
D30Benign neoplasm of urinary organs
D31Benign neoplasm of eye and adnexa
D32Benign neoplasm of meninges
D33Benign neoplasm of brain and oth prt central nervous system
D34Benign neoplasm of thyroid gland
D35Benign neoplasm of other and unspecified endocrine glands
D36Benign neoplasm of other and unspecified sites
D37-D48
Neoplasms of Uncertain Behavior, Polycythemia Vera and Myelodysplastic Syndromes
D37Neoplasm of uncrt behavior of oral cavity and dgstv organs
D38Neoplm of uncrt behav of mid ear & resp and intrathorac org
D39Neoplasm of uncertain behavior of female genital organs
D3ABenign neuroendocrine tumors
D40Neoplasm of uncertain behavior of male genital organs
D41Neoplasm of uncertain behavior of urinary organs
D42Neoplasm of uncertain behavior of meninges
D43Neoplasm of uncertain behavior of brain and cnsl
D44Neoplasm of uncertain behavior of endocrine glands
D45Polycythemia vera
D46Myelodysplastic syndromes
D47Oth neoplm of uncrt behav of lymphoid, hematpoetc & rel tiss
D48Neoplasm of uncertain behavior of other and unsp sites
D49-D49
Neoplasms of Unspecified Behavior
Frequently Asked Questions
What ICD-10 codes are in Chapter 2?
Chapter 2: Neoplasms covers ICD-10-CM codes C00-D49. It contains 18 code blocks with 140 top-level categories.
What conditions does ICD-10 Chapter 2 cover?
Includes all codes for cancer (malignant neoplasms), benign tumors, carcinoma in situ, and neoplasms of uncertain behavior. Common codes include breast cancer (C50), lung cancer (C34), prostate cancer (C61), and colon cancer (C18). This chapter is critical for oncology billing and cancer registry reporting. This chapter includes codes from C00-D49.
How many code blocks are in Chapter 2?
Chapter 2 has 18 code blocks: C00-C14 (Malignant Neoplasms of Lip, Oral Cavity and Pharynx), C15-C26 (Malignant Neoplasms of Digestive Organs), C30-C39 (Malignant Neoplasms of Respiratory and Intrathoracic Organs), C40-C41 (Malignant Neoplasms of Bone and Articular Cartilage), and 14 more.
Is there an ICD-11 equivalent of ICD-10 Chapter 2?
ICD-11 reorganizes many chapters compared to ICD-10. Some conditions in Chapter 2 may appear in different ICD-11 chapters. Use the ICD-10 to ICD-11 converter to find specific code equivalents.
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