Cross-Mappings

RxNorm

NLM's normalized vocabulary for clinical drugs, with stable RxCUI identifiers across brands, strengths, and dose forms.

Definition

RxNorm is the U.S. National Library of Medicine's normalized vocabulary for clinical drugs. Each entity is identified by an RxCUI (RxNorm Concept Unique Identifier), an integer that is stable across releases. Term types include Ingredient (IN), Brand Name (BN), Semantic Clinical Drug (SCD: ingredient + strength + dose form), Semantic Branded Drug (SBD), Generic Pack (GPCK), and Branded Pack (BPCK), among others.

RxNorm is the U.S. standard for prescription messaging in HL7 v2, FHIR Medication / MedicationRequest / MedicationStatement resources, and ePrescribing under SCRIPT. It is also linked to the FDA's NDC (National Drug Code) directory through RxNorm Mapping (RxMap) tables.

Because RxNorm participates in UMLS, RxCUIs share CUIs with their SNOMED CT and ICD-10 counterparts where appropriate. AutoICD uses RxNorm to link ICD-10 conditions to the medications most often prescribed for them and to support medication-aware coding workflows.

When to use

  • FHIR MedicationRequest.medicationCodeableConcept needs a normalized clinical drug identifier.
  • Medication reconciliation, drug-drug interaction checking, or formulary mapping.
  • Cross-walking from NDC codes to a normalized RxCUI for analytics.

Try it in AutoICD API

Browse RxNorm via the AutoICD reference API

curl https://autoicdapi.com/reference/rxnorm/197361 \
  -H "Authorization: Bearer $AUTOICD_API_KEY"

Language: bash. View full API docs · Get an API key.

Related concepts

Authoritative sources

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