ICD-10 codes for Fatigue
Fatigue is coded primarily under R53, R53.83, R53.81 in the ICD-10-CM (Clinical Modification) classification. Top-level categories include R53 (Malaise and fatigue). The 2025 ICD-10-CM code set includes 8 codes related to fatigue, of which 6 are billable (specific enough to appear on a medical claim).
Fatigue and malaise are coded under R53 in ICD-10-CM. R53.83 (other fatigue) and R53.81 (other malaise) are most commonly used. R53.82 covers chronic fatigue, unspecified, while G93.32 is myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), recognized as a distinct diagnosis.
Total Codes
8
Billable Codes
6
Categories
1
SNOMED CT Concepts
25+
Top 8 Relevant ICD-10 Codes
The codes most commonly assigned to fatigue, ranked by primary-match status, billable status, and specificity. Tap a code to see its full ICD-10 detail page.
Primary Code Categories
These are the top-level ICD-10-CM categories for fatigue. Click any code to see all specific subcodes within that group.
Billable / Specific Codes (6)
Specific ICD-10-CM codes that can be reported on medical claims for fatigue.
Cross-Mappings to Other Standards
ICD-10-CM codes for fatigue link to several adjacent terminologies. These mappings are precomputed from official sources (NLM RxNav, UMLS Metathesaurus, SNOMED CT International) and served via AutoICD's reference and translate APIs.
SNOMED CT
25+ concepts mapped from this code group. Concept IDs include 716749005, 1131000175106, 13791008, 148871000119109, ....
Browse SNOMED CT directoryUMLS Metathesaurus
16 CUIs indexed. Sample: C0024528, C2830451, C0004093, C3714552, ....
Browse UMLS directoryICD-11
ICD-11 (WHO 2022) classifies many of these conditions under different chapter and stem-code structures. Use the converter to see specific ICD-10 to ICD-11 mappings.
Open ICD-10 to ICD-11 converterFrequently Asked Questions
What is the ICD-10 code for fatigue?
The primary ICD-10-CM codes for fatigue are R53, R53.83, R53.81. Across all sub-categories, 8 codes are grouped under fatigue, with 6 marked as billable (specific enough for a medical claim).
How many ICD-10 codes are there for fatigue?
There are 8 ICD-10-CM codes related to fatigue. Of these, 6 are billable specific codes and 2 are non-billable header categories that organize the specific codes underneath them. Header codes cannot be reported on a claim by themselves.
Is there a billable ICD-10 code for fatigue?
Yes. 6 of the 8 ICD-10-CM codes for fatigue are billable. Common examples include R53.0 (Neoplastic (malignant) related fatigue); R53.1 (Weakness); R53.2 (Functional quadriplegia). Code to the highest level of specificity supported by the documentation.
Which fatigue ICD-10 code should I use for billing?
The most commonly used billable codes for fatigue include: R53.0 (Neoplastic (malignant) related fatigue); R53.1 (Weakness); R53.2 (Functional quadriplegia). The correct code depends on the documented clinical presentation, including any complications, episode (acute / chronic), and laterality where applicable. Always code to the highest level of specificity supported by the clinical documentation.
Is R53 a billable ICD-10 code?
No, R53 (Malaise and fatigue) is a non-billable header code. You need to use a more specific child code for billing purposes.
What are the SNOMED CT concepts for fatigue?
The ICD-10 codes for fatigue map to at least 25 SNOMED CT concepts. Examples of SNOMED CT concept IDs in this group include 716749005, 1131000175106, 13791008, 148871000119109, 16469991000119101. SNOMED CT is a clinical terminology used in electronic health records; AutoICD's coding API returns SNOMED CT IDs alongside each ICD-10 code via the include_snomed=true flag.
What UMLS Concept Unique Identifiers (CUIs) cover fatigue?
The ICD-10 codes for fatigue are linked to 16 UMLS CUIs in the National Library of Medicine's Metathesaurus. Sample CUIs include C0024528, C2830451, C0004093, C3714552, C2349677. UMLS CUIs unify the same concept across SNOMED CT, ICD-10, ICD-11, RxNorm, MeSH, and dozens of other source vocabularies.
What are other names for fatigue in ICD-10?
Fatigue may also be referred to as: fatigue, tiredness, weakness, asthenia, exhaustion, malaise. The same ICD-10-CM codes apply regardless of which term appears in the clinical documentation. Synonyms are surfaced by AutoICD's NER pass and mapped to the canonical ICD-10 family above.
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